返回列表National Rare Blood Bank of China Supplied Type p blood to Japanese Patient

来源: 时间:2017/7/5 9:46:39

Shanghai Blood Center (SBC) received an aid request from Japanese Red Cross Osaka Blood Center (OBC) on Oct 13, 2016. A Japanese patient with myelodysplastic syndrome (MDS) needed type p blood. Because of the illness condition, the patient needed multiple-transfusion. Though two local blood donors with type p were recruited in Japan, the blood supply could not meet the follow-up treatment of the patient.

 

Type p is a very rare blood type, only several cases with the blood type could be found among millions of people. Individuals with such blood type would easily produce an antibody during transfusion or pregnancy, which could react with almost all the human red blood cells (exception: type p RBCs). Once, the antibody combined with RBCs, it would accelerate the destruction of RBCs, resulting in acute hemolytic transfusion reactions, and endanger life safety. So the patient with type p and already had anti-p antibody, could only been given type p blood.

 

SBC is the location of National Rare Blood Bank of China (NRBBC) and is also a member of the Rare Blood Committee, International Society of Blood Transfusion. It has the responsibility and obligation to help and promote the sharing of rare blood in Asia.

 

After receiving the request for blood from OBC, The staffs of NRBBC immediately retrieved the rare blood database, and found three suitable donors in China. None of the three donors lived in Shanghai, the staffs of NRBBC contacted the blood centers for help, which were located the three donors’ residence place. Through the blood centers’ efforts, two volunteers were confirmed to be qualified blood donors, who were in Yulin, Guangxi, and Wuhan, Hubei, respectively.

 

According to the Japanese requirements, the blood needed to do Leukocyte filtration and Irradiation. The shelf life of Irradiation blood was only fourteen days, so after the blood collection and preparation, it must be promptly sent to Japan. This required us to prepare all the documents before blood collection. Any mistake in the links would delay the blood delivery, and lead to the waste of precious blood resources. With the help of Shanghai Entry-Exit Inspection and Quarantine Bureau, the exit approval of rare blood was gained successfully.

 

When determine the date of blood collection, we contacted the Japanese side to sign blood allocation agreement, prepare the blood entry and transport work. On the other hand, NRBBC started the blood allocation emergency program, send two staffs to Yulin Central Blood Station and Wuhan Blood Center to take blood. Fresh blood was prepared and tested immediately after collection. On Dec 21, 2016, 800 milliliters of type p blood was delivered to international transport companies. The blood arrived in Japan is in good condition. One month later, we received the feedback from Japanese, the patient successfully implemented two blood transfusion treatment with the two units of type p blood.

 

There are many successful cases of "rare blood type" resources off-site transportation to treat patients in China. In 2014 and 2015, Shanghai sent -D-, and Fya- blood to Beijing and Shenzhen, respectively; Jiangsu delivered p blood to Tianjin. All the patients were eventually treated successfully. There were lots of limiting factors, such as International application and transportation system, which hinder the international sharing of "rare blood type" resources, and some patients have not been able to get timely treatment.

 

In August, 2016, at the "Asian Rare Blood Seminar" held in Mongolia, rare blood group experts from Asian countries made suggestions on the promotion of regional cooperation and the protection of rare blood supply problems and challenges. A consensus was reached at meeting: in the next two years, to establish and improve procedure for the international application and transport for rare blood type blood among Asian countries gradually; to build an Asian rare blood mutual aid rescue network, open a green channel to provide an emergency blood life protection for Asians who have rare blood type. The type p blood sent to Osaka, Japan, was the first successful implementation of China to give blood support to foreign country, and helped NRBBC accumulated experience for international cooperation.